We employ the entropic uncertainty relations and the quantum Fisher information to explore the formation of quark $t\bar{t}$ pairs at a large hadron collider through the 

combination of $q\bar{q}$ pair and $gg$ pair initiated processes. A comprehensive analysis has been undertaken on the procedure of quark and gluon channel mixing in the 

production of top quark pairs $t\bar{t}$, encompassing the tightness of the entropic uncertainty inequalities and the maximum quantum Fisher information of the system.